Nanoparticel Tracking Analysis or Dynamic Light Scattering?

 
NTA or DLS ?
Nanoparticle Tracking Analysis or
Dynamic Light Scattering?
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Questions that helps illustrate the core of the issue of these two techniques:
• Since the Nanosight gives me particle concentration, it’s somewhat straightforward to calculate what % of my Nanoparticles are aggregated. Can I calculate % aggregated particles in the DLS as well?  Or does the varying amount of intensity, and the protein+nanoparticle mixture in the sample confound that calculation?
• If I wanted to measure non-spherical particles (for example nanorods), which system would give me a more accurate diffusion coefficient/size?
 The NanoSight utilizes the technique of Nanoparticle Tracking Analysis(NTA) where the trajectories of individual scattering objects are observed under a microscope and their displacement related to each object’s size.  The Zetasizer Nano utilizes the technique of Dynamic Light Scattering (DLS, also known as PCS and QELS) where the intensity fluctuations in the scattered light are analyzed and related to the diffusion of the scattering objects.
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